Fibroblast is the basic cell of the connective tissue and its shape is flat, long and oval. It may have 1-2 nuclei, its cytoplasm is extended and, like every cell, it has very important functions in the organism. The most important of these is to create the structure in which the cells are located. Namely, this intercellular structure that gives shine, softness and flexibility to the skin consists of collagen and elastin. The task of fibroblasts is to produce these substances that are extremely important for the skin. Another important function of the fibroblast is to activate the organism’s wound-healing system when there is an injury to the skin.
Over time, fibroblasts in the organism lose the ability to produce collagen and elastin. Fibroblasts, especially in the sun-exposed part of the skin, are damaged by effects such as radioactivity in sunlight and their numbers decrease over time. As a result, the skin loses its vitality, collapses, sags and wrinkles begin to form. In order to eliminate these negative effects, it is necessary to give the skin fibroblasts that do their job correctly. If fibroblasts are taken from another person, the organism will perceive these cells as foreign and try to get rid of them. Naturally, giving fibroblast cells taken from the person’s own self is the best solution.
Fibroblast treatment for hair loss utilizes the regenerative properties of fibroblast cells to promote hair growth and improve the condition of the scalp. The treatment typically involves harvesting fibroblast cells from the patient’s own body or using laboratory-cultured fibroblasts to stimulate hair follicles and enhance hair regeneration.
How Fibroblast Treatment Works:
- Cell Harvesting: Fibroblast cells can be harvested from the patient’s own skin (autologous fibroblasts) or cultured in a laboratory setting.
- Preparation: The harvested or cultured fibroblast cells are prepared and processed to concentrate them into a solution or suspension.
- Application: The concentrated fibroblast solution is then injected or applied directly to the scalp using microinjections or a microneedling technique. This allows the fibroblast cells to penetrate into the scalp tissue and interact with hair follicles.
Mechanism of Action:
- Collagen Production: Fibroblasts are known for their role in producing collagen and other extracellular matrix components. Increased collagen production can improve scalp health and support hair follicle function.
- Stimulation of Hair Follicles: By enhancing the local environment around hair follicles, fibroblast treatment is believed to stimulate dormant hair follicles, promote new hair growth, and improve hair thickness and density.
How we do fibroblast treatment? After tissue biopsy is taken and fibroblast cells are multiplied, the resulting cell-rich solution is injected into the areas where collagen production will be stimulated. The application is carried out in 3 sessions, 3-4 weeks apart.
Is Fibroblast Treatment Continuous?
Although it varies depending on the patient, the first effects begin to be seen after the second injection. There are also patients in whom the effect is visible immediately after the first injection. The effect continues to gradually increase for up to 12 months. Healing and effect are long-lasting and according to research, it varies between 4-5 years.