SVF is a cell population derived from adipose tissue, which includes a mixture of adipose-derived stem cells (ADSCs), endothelial cells, pericytes, immune cells, and other stromal cells. It is obtained by enzymatic digestion and centrifugation of harvested fat tissue. SVF is rich in regenerative cells and growth factors, making it a valuable resource for regenerative medicine applications. SVF has been explored for its potential therapeutic benefits in tissue regeneration, wound healing, orthopedic conditions, and aesthetic procedures.
Stromal Vascular Fraction (SVF) therapy for hair loss is a regenerative treatment that involves using a concentrated mixture of cells derived from adipose (fat) tissue to stimulate hair growth and improve hair density. Here’s an overview of what SVF therapy entails, how it works, and its potential benefits:
What is Stromal Vascular Fraction (SVF)?
Stromal Vascular Fraction (SVF) refers to a mixture of cells that are obtained from the stromal vascular fraction of adipose tissue. This fraction includes various cell types such as adipose-derived stem cells (ADSCs), endothelial cells, pericytes, and immune cells. SVF is rich in growth factors, cytokines, and other bioactive molecules that play crucial roles in tissue repair, regeneration, and immune modulation.
How SVF Therapy for Hair Loss Works:
- Harvesting of Adipose Tissue: A small amount of fat tissue is typically harvested from the patient’s abdomen or thighs through a minimally invasive liposuction procedure.
- Processing and Isolation of SVF: The harvested fat tissue undergoes processing to isolate the SVF, which involves separating the stromal vascular cells from the adipocytes (fat cells).
- Preparation and Application: The isolated SVF, which contains a concentrated mix of cells and growth factors, is then prepared for application to the scalp.
- Application to the Scalp: SVF can be administered to the scalp through:
- Injections: Direct injection into the scalp where hair loss is present.
- Topical Application: Application via a serum or solution directly to the scalp, often combined with microneedling to enhance absorption.
Mechanism of Action:
- Stem Cell Activity: ADSCs within SVF have the potential to differentiate into various cell types, including those involved in hair follicle regeneration.
- Growth Factors and Cytokines: SVF is rich in growth factors (such as VEGF, PDGF, FGF) and cytokines that promote angiogenesis (formation of new blood vessels) and stimulate hair follicle growth.
- Anti-inflammatory Effects: SVF has been shown to possess anti-inflammatory properties, which can help create a more favorable environment for hair growth.